Price varies based on number of clients, MSRP starts at $499 for KMS + 10 clients.
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Webmail implementation is one of the best available on the Mac or any other platform
Wider range of direct client support than other similar products on the Mac
Integrates into Active Directory and Open Directory environments
Admin tools are both intuitive and powerful
Supports CalDAV, LDAP address books, Public/Shared mail/calendar/contact folders, IMAP/POP/SMTP/HTTP-DAV, and Exchange Active Sync for iPhone and other mobile devices
Web administration feature set is severely limited compared to fat administration client
Outlook support via plug-in that requires updating with new KMS releases
Directory support via separate installs
Odd iCal issues
No Kerberos/SSO client support
More expensive than Mac OS X 10.6 Server's groupware offering
You can't use Mac OS X 10.6's Exchange support with KMS
Can have scaling issues, especially for large numbers of Entourage users